VAMP2

Also known as SYB2, VAMP-2, vesicle associated membrane protein 2, NEDHAHM

gen de la especie Homo sapiens

In the Vinony graph

Within Vinony's link graph, VAMP2 is referenced by 87 other articles, and connects out to COPII, AP-type membrane coat adaptor complex and PubMed.

It is catalogued under topics including Genes on human chromosome 17 and Neural synapse.

Its subject is documented across 4 Wikipedia language editions.

Gene data

VAMP2

Name: vesicle associated membrane protein 2
Type: protein-coding
Position: 8,159,149–8,163,584 (−)
Aliases: NEDHAHM, SYB2, VAMP-2
Ensembl: ENSG00000220205
RefSeq RNA: NM_001330125.1, NM_014232.3
RefSeq protein: NP_001317054.1, NP_055047.2

The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq, Jul 2008].