VMP1

Also known as EPG3, TANGO5, TMEM49, vacuole membrane protein 1

Vacuole membrane protein 1 is a protein that in humans is encoded by the VMP1 gene.

Gene data

VMP1

Name: vacuole membrane protein 1
Type: protein-coding
Aliases: EPG3, TANGO5, TMEM49

This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy. [provided by RefSeq, Jul 2016].

via MyGene.info