VMP1
Sign in to saveAlso known as EPG3, TANGO5, TMEM49, vacuole membrane protein 1
Vacuole membrane protein 1 is a protein that in humans is encoded by the VMP1 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to VMP1, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 17.
Vinony links it to 5 Wikipedia language editions.
Gene data
VMP1- Name
- vacuole membrane protein 1
- Type
- protein-coding
- Position
- 59,707,192–59,842,255 (+)
- Aliases
- EPG3, TANGO5, TMEM49
- Ensembl
- ENSG00000062716
- RefSeq RNA
- NM_001329394.2, NM_001329395.2, NM_001329396.2, NM_001329397.2, NM_001329398.2
- RefSeq protein
- NP_001316323.1, NP_001316324.1, NP_001316325.1, NP_001316326.1, NP_001316327.1
This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy. [provided by RefSeq, Jul 2016].
Gene Ontology
Biological process
via MyGene.info
Gene · Ensembl
vacuole membrane protein 1
- Symbol
- VMP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:59,707,192-59,842,255
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 23686
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/81671
- genomic end
- 57919616
- genomic start
- 57784553
- chromosome
- human chromosome 17
- cytogenetic location
- 17q23.1
- expressed in
- appendix
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Vacuole membrane protein 1 is a protein that in humans is encoded by the VMP1 gene.
==References==
Excerpted from Wikipedia’s “VMP1” article, available under the CC BY-SA 4.0 licence.