WDR77

Also known as MEP-50, MEP50, Nbla10071, p44, p44/Mep50, HKMT1069, WD repeat domain 77

protein-coding gene in the species Homo sapiens

Gene data

WDR77

Name: WD repeat domain 77
Type: protein-coding
Aliases: HKMT1069, MEP-50, MEP50, Nbla10071, p44, p44/Mep50

The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].

via MyGene.info