WNT10A
Sign in to saveAlso known as OODD, SSPS, STHAG4, Wnt family member 10A
Wnt-10a is a protein that in humans is encoded by the WNT10A gene.
Gene data
WNT10A- Name
- Wnt family member 10A
- Type
- protein-coding
- Position
- 218,880,852–218,899,581 (+)
- Aliases
- ECTD16, OODD, SSPS, STHAG4
- Ensembl
- ENSG00000135925
- RefSeq RNA
- NM_025216.3, XM_011511929.3, XM_011511930.2, XM_054344057.1, XM_054344058.1
- RefSeq protein
- NP_079492.2, XP_011510231.1, XP_011510232.1, XP_054200032.1, XP_054200033.1
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Wikidata facts
Show 5 more facts
- exact match
- identifiers.org/ncbigene/80326
- HomoloGene ID
- 22525
- genomic end
- 219764303
- genomic start
- 218880852
- cytogenetic location
- 2q35
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Wnt-10a is a protein that in humans is encoded by the WNT10A gene.
== Function ==