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GeneQ18032367· pop 6· linked from 27 articles

WNT10B

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Also known as SHFM6, WNT-12, Wnt family member 10B, STHAG8

Protein Wnt-10b (formerly Wnt12) is a protein that in humans is encoded by the WNT10B gene.

Gene data

WNT10B
Name
Wnt family member 10B
Type
protein-coding
Position
48,965,185–48,972,669 (−)
Aliases
SHFM6, STHAG8, WNT-12
Ensembl
ENSG00000169884
RefSeq RNA
NM_003394.4
RefSeq protein
NP_003385.2

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

mTOR signaling pathway - Homo sapiens (human)Wnt signaling pathway - Homo sapiens (human)Hippo signaling pathway - Homo sapiens (human)Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)Melanogenesis - Homo sapiens (human)Cushing syndrome - Homo sapiens (human)Alzheimer disease - Homo sapiens (human)Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)Human papillomavirus infection - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

Wnt family member 10B

Symbol
WNT10B
Biotype
Protein coding
Organism
Homo sapiens
Location
12:48,965,185-48,972,669
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/7480
HomoloGene ID
20721
genomic end
48971735
genomic start
49359123
chromosome
human chromosome 12
cytogenetic location
12q13.12
expressed in
entorhinal cortex
Sources (5)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Protein Wnt-10b (formerly Wnt12) is a protein that in humans is encoded by the WNT10B gene.

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis.

Excerpted from Wikipedia’s “WNT10B” article, available under the CC BY-SA 4.0 licence.

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via Wikidata sitelinks · CC0