YWHAB
Sign in to saveAlso known as GW128, HEL-S-1, HS1, KCIP-1, YWHAA, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
14-3-3 protein beta/alpha is a protein that in humans is encoded by the YWHAB gene.
Gene data
YWHAB- Name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
- Type
- protein-coding
- Position
- 44,885,676–44,908,715 (+)
- Aliases
- GW128, HEL-S-1, HS1, KCIP-1, YWHAA
- Ensembl
- ENSG00000166913
- RefSeq RNA
- NM_003404.5, NM_139323.4, XM_017028040.2, XM_054323962.1
- RefSeq protein
- NP_003395.1, NP_647539.1, XP_016883529.1, XP_054179937.1
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
- Symbol
- YWHAB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:44,885,676-44,908,715
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein YWHAB PDB 2bq0.png
Show 5 more facts
- HomoloGene ID
- 20724
- exact match
- identifiers.org/ncbigene/7529
- genomic end
- 43537173
- genomic start
- 44885702
- cytogenetic location
- 20q13.12
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
14-3-3 protein beta/alpha is a protein that in humans is encoded by the YWHAB gene.
== Function ==