1,3-dichloro-2-propanol

Also known as 1,3-DCP, alpha-dichlorohydrin, sym-glycerol dichlorohydrin, 2-chloro-1-(chloromethyl)ethanol, 1,3-dichloropropan-2-ol, alpha,gamma-dichlorohydrin, glycerol 1,3-dichlorohydrin, 1,3-dichloro-1,3-dideoxyglycerol

1,3-Dichloropropan-2-ol (1,3-DCP) is an organic compound with the formula HOCH2CHClCH2Cl. It is a colorless liquid. It is an intermediate in the production of epichlorohydrin.

Research

142 papers

1,3-Dichloro-2-propanol induced ferroptosis through Nrf2/ARE signaling pathway in hepatocytes.Environmental toxicology · 2022
1,3-Dichloro-2-propanol-Induced Renal Tubular Cell Necroptosis through the ROS/RIPK3/MLKL Pathway.Journal of agricultural and food chemistry · 2022
Diallyl disulfide prevents 1,3-dichloro-2-propanol-induced hepatotoxicity through mitogen-activated protein kinases signaling.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022
1,3-dichloro-2-propanol induced lipid accumulation by blocking autophagy flux in HepG2 cells.Toxicology · 2021
1,3-dichloro-2-propanol caused lipid droplets accumulation by suppressing neutral lipases via BMAL1 in hepatocytes.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023

via PubMed

Article

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References

1,3-Dichloropropan-2-ol (1,3-DCP) is an organic compound with the formula HOCH2CHClCH2Cl. It is a colorless liquid. It is an intermediate in the production of epichlorohydrin.

1,3-DCP is a believed to be a carcinogen and mutagen. The International Agency for Research on Cancer classifies it as a Group 2B carcinogen ("possibly carcinogenic to humans").