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2,2,2-trichloroethanol
Sign in to saveAlso known as 2,2,2-trichloro-1-ethanol
2,2,2-Trichloroethanol is the chemical compound with formula . Its molecule can be described as that of ethanol, with the three hydrogen atoms at position 2 (the methyl group) replaced by chlorine atoms. It is a clear flammable liquid at room temperature, colorless when pure but often with a light yellow color.
Chemical data
- Formula
- C2H3Cl3O
- Molecular weight
- 149.4 g/mol
- IUPAC name
- 2,2,2-trichloroethanol
- SMILES
- C(C(Cl)(Cl)Cl)O
- InChIKey
- KPWDGTGXUYRARH-UHFFFAOYSA-N
- XLogP
- 1.4
- Polar surface area
- 20.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 147.925
Show 5 more facts
- chemical formula
- C₂H₃Cl₃O
- pKa
- 12.24
- canonical SMILES
- C(C(Cl)(Cl)Cl)O
- melting point
- 18.0
- Commons category
- 2,2,2-Trichloroethanol
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Use in organic synthesis
- See also
- References
2,2,2-Trichloroethanol is the chemical compound with formula . Its molecule can be described as that of ethanol, with the three hydrogen atoms at position 2 (the methyl group) replaced by chlorine atoms. It is a clear flammable liquid at room temperature, colorless when pure but often with a light yellow color.
The pharmacological effects of this compound in humans are similar to those of its prodrug chloral hydrate, and of chlorobutanol. Historically, it has been used as a sedative hypnotic. The hypnotic drug triclofos (2,2,2-trichloroethyl phosphate) is metabolized in vivo to 2,2,2-trichloroethanol. Chronic exposure may result in kidney and liver damage.
Excerpted from Wikipedia’s “2,2,2-trichloroethanol” article, available under the CC BY-SA 4.0 licence.