Structure via PubChem · Public domain (PubChem)
2,3-dichlorophenylpiperazine
Sign in to save2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound from the phenylpiperazine family. It is both a precursor in the synthesis of aripiprazole and one of its metabolites. It is unclear whether 2,3-DCPP is pharmacologically active as a serotonin receptor agonist similar to its close analogue 3-chlorophenylpiperazine (mCPP), though it has been shown to act as a partial agonist of the dopamine D2 and D3 receptors.
In the Vinony graph
Vinony's link graph records 532 inbound references to 2,3-dichlorophenylpiperazine, and connects out to 1-phenylpiperazine, m-chlorophenylpiperazine and quipazine.
It is catalogued under topics including 1-Phenylpiperazines, 2,3-Dichlorophenylpiperazines and Chemical articles with multiple compound IDs.
Vinony links it to 7 Wikipedia language editions.
Chemical data
- Formula
- C10H12Cl2N2
- Molecular weight
- 231.12 g/mol
- IUPAC name
- 1-(2,3-dichlorophenyl)piperazine
- SMILES
- C1CN(CCN1)C2=C(C(=CC=C2)Cl)Cl
- InChIKey
- UDQMXYJSNNCRAS-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 15.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 230.038
Show 3 more facts
- chemical formula
- C₁₀H₁₂Cl₂N₂
- canonical SMILES
- C1CN(CCN1)C2=C(C(=CC=C2)Cl)Cl
- topic's main category
- Category:2,3-Dichlorophenylpiperazines
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
7 sectionsContents
- Legality
- List of derivatives
- Positional Isomer
- Triple Substituted
- See also
- References
- External links
2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound from the phenylpiperazine family. It is both a precursor in the synthesis of aripiprazole and one of its metabolites. It is unclear whether 2,3-DCPP is pharmacologically active as a serotonin receptor agonist similar to its close analogue 3-chlorophenylpiperazine (mCPP), though it has been shown to act as a partial agonist of the dopamine D2 and D3 receptors.
==Legality== 2,3-DCPP has been made illegal in Japan and Hungary after having been identified in seized designer drug samples.
Excerpted from Wikipedia’s “2,3-dichlorophenylpiperazine” article, available under the CC BY-SA 4.0 licence.