Also known as 2-Amino-5-chlorotoluene, 4-Chloro-o-toluidine
'4-Chloro-o-toluidine (4-COT, 4-chloro-2-methylaniline') is the organic compound with the formula CH3C6H3Cl(NH2). It is a colorless solid. The compound is produced as an intermediate to the pesticide chlordimeform and a precursor to some azo dyes. Production has declined after it was shown to be highly carcinogenic.
'4-Chloro-o-toluidine (4-COT, 4-chloro-2-methylaniline') is the organic compound with the formula CH3C6H3Cl(NH2). It is a colorless solid. The compound is produced as an intermediate to the pesticide chlordimeform and a precursor to some azo dyes. Production has declined after it was shown to be highly carcinogenic.
== Production and use == It is produced by the chlorination reaction of N-acetyltoluidine followed by deprotection and separation from the 6-chloro isomer. Production of 4-chloro-o-toluidine began in Germany in 1924. In Switzerland, 4-COT and its salts were produced between 1956 and 1976. Production and distribution ceased in 1979 in the US and in 1986 in Germany.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).