Structure via PubChem · Public domain (PubChem)
4-Me-αMT
Sign in to saveAlso known as 4-methyl-AMT, 4,α-dimethyltryptamine, 4,α-DMT, MP-809, 4-Methyl-α-methyltryptamine
4-Me-αMT (developmental code name MP-809), or 4-Me-AMT, also known as 4-methyl-α-methyltryptamine or as 4,α-dimethyltryptamine (4,α-DMT), is an experimental antidepressant of the tryptamine and α-alkyltryptamine families that was never marketed. It is closely structurally related to serotonergic psychedelics and entactogens like α-methyltryptamine (αMT) and α-ethyltryptamine (αET).
Chemical data
- Formula
- C12H16N2
- Molecular weight
- 188.27 g/mol
- IUPAC name
- (2S)-1-(4-methyl-1H-indol-3-yl)propan-2-amine
- SMILES
- CC1=C2C(=CC=C1)NC=C2C[C@H](C)N
- InChIKey
- KEOYEGHPRBDSKD-VIFPVBQESA-N
- XLogP
- 2.2
- Polar surface area
- 41.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 188.131348512
Show 4 more facts
- chemical formula
- C₁₂H₁₆N₂
- canonical SMILES
- CC1=C2C(=CC=C1)NC=C2CC(C)N
- isomeric SMILES
- Cc1cccc2[nH]cc(C[C@H](C)N)c12
- Commons category
- 4-Me-αMT
via Wikidata · CC0
~2 min read
Encyclopedic overview
10 sectionsContents
- Use and effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Chemistry
- Analogues
- History
- See also
- References
- External links
4-Me-αMT (developmental code name MP-809), or 4-Me-AMT, also known as 4-methyl-α-methyltryptamine or as 4,α-dimethyltryptamine (4,α-DMT), is an experimental antidepressant of the tryptamine and α-alkyltryptamine families that was never marketed. It is closely structurally related to serotonergic psychedelics and entactogens like α-methyltryptamine (αMT) and α-ethyltryptamine (αET).
==Use and effects== 4-Me-αMT is active at a dose of 20 to 60mg orally in humans, though described as being an antidepressant rather than a hallucinogen. It was found to be effective as an antidepressant in preliminary clinical studies. Alexander Shulgin has said that 4-Me-αMT produced some feelings of unreality at 20mg, as well as skin flushing, muscle tightness, and mydriasis. However, he has said that it could not be called a hallucinogen at assessed doses and has listed the hallucinogenic dose as being greater than 60mg.
Excerpted from Wikipedia’s “4-Me-αMT” article, available under the CC BY-SA 4.0 licence.