indopan
Sign in to saveAlso known as 164E, 3-IT, AMT, IT-290, IT-403, αMT, 1-(1H-Indol-3-yl)-2-propanamine
α-Methyltryptamine (αMT, AMT) is a psychedelic, stimulant, and entactogen drug of the tryptamine and α-alkyltryptamine families. It was originally developed as an antidepressant at Upjohn in the 1960s, and was used briefly as an antidepressant in the Soviet Union under the brand name Indopan or Indopane before being discontinued.
Key facts
- Drug.legal_CA
- Unscheduled
- Drug.legal_UK
- Class A
- Drug.legal_US
- Schedule I
- Drug.legal_DE
- Anlage I
- Drug.onset
- 3–4hours
- Drug.duration_of_action
- 12–24hours
- Drug.CAS_number
- 299-26-3
- Drug.ATC_prefix
- None
- Drug.PubChem
- 9287
- Drug.DrugBank
- DB01446
- Drug.KEGG
- C20127
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443378813
- Drug.drug_name
- α-Methyltryptamine
- Drug.image
- AMT.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 185px
- Drug.image2
- Alpha-Methyltryptamine-3d-sticks.png
via Wikipedia infobox
Wikidata facts
- Mass
- 174.115698
Show 3 more facts
- chemical formula
- C₁₁H₁₄N₂
- canonical SMILES
- CC(CC1=CNC2=CC=CC=C21)N
- Commons category
- Alpha-Methyltryptamine
via Wikidata · CC0
~12 min read
Article
35 sectionsContents
- Use and effects
- Side effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Monoamine oxidase inhibition
- Serotonergic neurotoxicity
- Pharmacokinetics
- Chemistry
- Synthesis
- Analogues
- History
- Society and culture
- Names
- Legal status
- Australia
- Austria
- Canada
- China
- Denmark
- Finland
- Germany
- Hungary
- Lithuania
- Slovakia
- Slovenia
- Spain
- Sweden
- United Kingdom
- United States
- Research
- See also
- Notes
- References
- External links
α-Methyltryptamine (αMT, AMT) is a psychedelic, stimulant, and entactogen drug of the tryptamine and α-alkyltryptamine families. It was originally developed as an antidepressant at Upjohn in the 1960s, and was used briefly as an antidepressant in the Soviet Union under the brand name Indopan or Indopane before being discontinued.
Side effects of αMT include agitation, restlessness, confusion, lethargy, pupil dilation, jaw clenching, and rapid heart rate, among others. αMT acts as a releasing agent of serotonin, norepinephrine, and dopamine, as a serotonin receptor agonist, and as a weak monoamine oxidase inhibitor. αMT is a substituted tryptamine and is closely related to α-ethyltryptamine (αET) and other α-alkylated tryptamines.