Structure via PubChem · Public domain (PubChem)
5S-HETE
Sign in to saveAlso known as 5-(S)-hydroxyeicosatetraenoic acid, 6,8,11,14-Eicosatetraenoic acid, 5-hydroxy-, (S-(E,Z,Z,Z))-, (5S,6E,8Z,11Z,14Z)-5-hydroxyeicosa-6,8,11,14-tetraenoic acid, (S)-(E,Z,Z,Z)-5-hydroxyeicosa-6,8,11,14-tetraenoic acid, 5(S)-hydroxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid, 5(S)-hydroxyeicosatetraenoic acid, 5-Hydroxyeicosatetraenoate, 5(S)-Hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid
chemical compound. this family of metabolites serve as hormone-like autocrine and paracrine signalling agents that contribute to the up-regulation of acute inflammatory and allergic responses.
Chemical data
- Formula
- C20H32O3
- Molecular weight
- 320.5 g/mol
- IUPAC name
- (5S,6E,8Z,11Z,14Z)-5-hydroxyicosa-6,8,11,14-tetraenoic acid
- SMILES
- CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)O
- InChIKey
- KGIJOOYOSFUGPC-JGKLHWIESA-N
- XLogP
- 5.2
- Polar surface area
- 57.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 320.235145
Show 6 more facts
- subject has role
- primary metabolite
- chemical formula
- C₂₀H₃₂O₃
- canonical SMILES
- CCCCCC=CCC=CCC=CC=CC(CCCC(=O)O)O
- isomeric SMILES
- CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](CCCC(=O)O)O
- found in taxon
- Homo sapiens
- physically interacts with
- Transient receptor potential cation channel subfamily V member 1
Sources (2)
via Wikidata · CC0