Skip to content
Vinony
English
EnglishDeutschEspañolFrançaisItalianoNederlandsPortuguêsSvenska
GeneQ18026398· pop 5· linked from 486 articles

GPR31

Sign in to save

Also known as 12-HETER, HETER, HETER1, G protein-coupled receptor 31

G-protein coupled receptor 31 also known as 12-(S)-HETE receptor is a protein that in humans is encoded by the GPR31 gene. The human gene is located on chromosome 6q27 and encodes a G-protein coupled receptor protein composed of 319 amino acids.

Gene data

GPR31
Name
G protein-coupled receptor 31
Type
protein-coding
Position
167,155,247–167,157,980 (−)
Aliases
12-HETER, HETER, HETER1
Ensembl
ENSG00000120436
RefSeq RNA
NM_005299.3
RefSeq protein
NP_005290.2

Enables G protein-coupled receptor activity and arachidonic acid binding activity. Involved in G protein-coupled receptor signaling pathway and response to acidic pH. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Pathways

Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)GPCR downstream signallingG alpha (i) signalling eventsFree fatty acid receptorsGPCR ligand bindingGPCRs, Class A Rhodopsin-like

via MyGene.info

Gene · Ensembl

G protein-coupled receptor 31

Symbol
GPR31
Biotype
Protein coding
Organism
Homo sapiens
Location
6:167,155,247-167,157,980
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
48337
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/2853
genomic end
167157980
genomic start
167155247
chromosome
human chromosome 6
cytogenetic location
6q27
expressed in
spleen
Sources (3)

via Wikidata · CC0

~6 min read

Encyclopedic overview

10 sections
Contents
  • Function
  • Ligand binding and activation
  • Signaling pathways
  • Additional receptors activated by 12(S)-HETE
  • Complications in determining GPR31 function
  • Tissue distribution
  • Clinical significance
  • Prostate cancer
  • Other diseases
  • References

G-protein coupled receptor 31 also known as 12-(S)-HETE receptor is a protein that in humans is encoded by the GPR31 gene. The human gene is located on chromosome 6q27 and encodes a G-protein coupled receptor protein composed of 319 amino acids.

== Function ==

Excerpted from Wikipedia’s “GPR31” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0