acepromazine
Sign in to saveAcepromazine, acetopromazine, or acetylpromazine (commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2, number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was used in humans during the 1950s as an antipsychotic, but is now almost exclusively used on animals as a sedative and antiemetic. A closely related analogue, chlorpromazine, is still used in humans.
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 477238349
- Drug.IUPAC_name
- 1-{10-[3-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}ethanone
- Drug.image
- Acepromazine.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Atravet, Acezine 2
- Drug.legal_AU
- S4
- Drug.legal_BR
- C1
- Drug.legal_CA
- OTC
- Drug.legal_US
- Rx-only
- Drug.bioavailability
- 6.6 L/kg, high volume of distribution
- Drug.elimination_half life
- 3 hours in horses, 15.9 hours in canines
- Drug.excretion
- urine
- Drug.CAS_number
- 61-00-7
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- AA04
- Drug.PubChem
- 6077
- Drug.DrugBank
- DB01614
via Wikipedia infobox
Article
9 sectionsContents
- Pharmacology
- Veterinary use
- Canine and feline
- Adverse effects in cats
- Adverse effects in dogs
- Dogs with a mutation in the ''ABCB1'' (''MDR1'') gene
- Equine
- Adverse effects
- References
{{Infobox drug | Watchedfields = changed | verifiedrevid = 477238349 | IUPAC_name = 1-{10-[3-(Dimethylamino)propyl]-10H-phenothiazin-2-yl}ethanone | image = Acepromazine.svg | image_class = skin-invert-image
| tradename = Atravet, Acezine 2 | Drugs.com = | legal_AU = S4 | legal_BR = C1 | legal_BR_comment = | legal_CA = OTC | legal_US = Rx-only | legal_UK = POM | legal_status = | routes_of_administration = IV, IM, SQ, oral