Structure via PubChem · Public domain (PubChem)
mosapramine
Sign in to saveMosapramine (Cremin) is an atypical antipsychotic used in Japan for the treatment of schizophrenia. It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 receptors.
Chemical data
- Formula
- C28H35ClN4O
- Molecular weight
- 479.1 g/mol
- IUPAC name
- 1'-[3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]spiro[1,5,6,7,8,8a-hexahydroimidazo[1,2-a]pyridine-3,4'-piperidine]-2-one
- SMILES
- C1CCN2C(C1)NC(=O)C23CCN(CC3)CCCN4C5=CC=CC=C5CCC6=C4C=C(C=C6)Cl
- InChIKey
- PXUIZULXJVRBPC-UHFFFAOYSA-N
- XLogP
- 5.4
- Polar surface area
- 38.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- psychosis
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 478.25
Show 3 more facts
- chemical formula
- C₂₈H₃₅ClN₄O
- canonical SMILES
- C1CCN2C(C1)NC(=O)C23CCN(CC3)CCCN4C5=CC=CC=C5CCC6=C4C=C(C=C6)Cl
- Commons category
- Mosapramine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Mosapramine (Cremin) is an atypical antipsychotic used in Japan for the treatment of schizophrenia. It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 receptors.
== See also == Carpipramine Clocapramine Fluspirilene (typical antipsychotic) Imidazopyridine
Excerpted from Wikipedia’s “mosapramine” article, available under the CC BY-SA 4.0 licence.