thumb|class=skin-invert-image|General structure of a 1,2-acetonide. The diol is shown in blue, the [[acetone part in red.]]
thumb|class=skin-invert-image|General structure of a 1,2-acetonide. The diol is shown in blue, the [[acetone part in red.]]
In organic chemistry, an acetonide is the functional group composed of the cyclic ketal of a diol with acetone. The more systematic name for this structure is an isopropylidene ketal. Acetonide is a common protecting group for 1,2- and 1,3-diols. The protecting group can be removed by hydrolysis of the ketal using dilute aqueous acid.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).