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fluocinolone

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EntityQ27106662· pop 7· linked from 272 articles

fluocinolone

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Fluocinolone is a synthetic glucocorticoid corticosteroid which was never marketed. The acetonide cyclic ketal of fluocinolone, fluocinolone acetonide, in contrast, has been marketed.

Chemical data

Formula
C21H26F2O6
Molecular weight
412.4 g/mol
IUPAC name
(6S,8S,9R,10S,11S,13S,14S,16R,17S)-6,9-difluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
SMILES
C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O
InChIKey
UUOUOERPONYGOS-CLCRDYEYSA-N
XLogP
1.1
Polar surface area
115 Ų
H-bond donors
4
H-bond acceptors
8
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 1
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
412.169745
Show 4 more facts
canonical SMILES
CC12CC(C3(C(C1CC(C2(C(=O)CO)O)O)CC(C4=CC(=O)C=CC43C)F)F)O
chemical formula
C₂₁H₂₆F₂O₆
isomeric SMILES
C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)C[C@@H](C4=CC(=O)C=C[C@@]43C)F)F)O
Commons category
Fluocinolone
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

1 sections
Contents
  • References

Fluocinolone is a synthetic glucocorticoid corticosteroid which was never marketed. The acetonide cyclic ketal of fluocinolone, fluocinolone acetonide, in contrast, has been marketed.

==References==

Excerpted from Wikipedia’s “fluocinolone” article, available under the CC BY-SA 4.0 licence.

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