adrenergic receptor
Sign in to saveAlso known as catecholamine receptor, Adrenoceptor family, ADR_fam, IPR002233
class of G protein-coupled receptors
Research
87,217 papers- Alpha-adrenergic receptor subtypes.The New England journal of medicine · 1980
- Adrenergic-receptor polymorphisms and heart failure.The New England journal of medicine · 2002
- Alterations in adrenergic receptor signaling in heart failure.Heart failure reviews · 2000
- α(2C)-Adrenergic Receptor Blockade Inhibits Langendorff-Isolated Rat Heart Work.Bulletin of experimental biology and medicine · 2023
- Radioligand Binding to Quantify Adrenergic Receptor Expression in the Heart.Current protocols · 2023
via PubMed
~14 min read
Encyclopedic overview
β2 adrenoceptor (PDB: 2rh1) shown binding carazolol (yellow) on its extracellular site. β2 stimulates cells to increase energy production and utilization. The membrane the receptor is bound to in cells is shown with a gray stripe.
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β2) agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example.
Excerpted from Wikipedia’s “adrenergic receptor” article, available under the CC BY-SA 4.0 licence.