metaraminol
Sign in to saveAlso known as 1-(m-mydroxyphenyl)-2-amino-1-propanol, 2-amino-1-(m-hydroxyphenyl)-1-propanol, 1-metaraminol, metaradrine, m-hydroxy norephedrine, alpha-(1-aminoethyl)-3-hydroxybenzenemethanol, (-)-erythro-metaraminol, m-hydroxypropadrine
Metaraminol, also known as metaradrine and sold under the brand name Aramine among others, is a sympathomimetic medication which is used in the prevention and treatment of hypotension (low blood pressure), particularly as a complication of anesthesia. It is given by intramuscular or intravenous administration.
Key facts
- Drug.Verifiedfields
- verified
- Drug.verifiedrevid
- 462249333
- Drug.image
- Metaraminol structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250px
- Drug.tradename
- Aramine, Metaramin, Pressonex, others
- Drug.DailyMedID
- Metaraminol
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- Intramuscular injection, intravenous administration
- Drug.class
- Norepinephrine releasing agent; Adrenergic receptor agonist; Sympathomimetic; Antihypotensive
- Drug.ATC_prefix
- C01
- Drug.ATC_suffix
- CA09
- Drug.legal_AU
- S4
- Drug.legal_UK
- POM
- Drug.legal_US
- Rx-only
- Drug.protein_bound
- 45%
- Drug.metabolism
- Liver
- Drug.CAS_number
- 54-49-9
via Wikipedia infobox
Research
1,206 papers- Metaraminol use during spinal anaesthesia for caesarean section: a meta-analysis of randomised controlled trials.International journal of obstetric anesthesia · 2019
- BET 3: Peripheral metaraminol infusion in the emergency department.Emergency medicine journal : EMJ · 2017
- Rational use of metaraminol can improve pharmaceutical care.European journal of hospital pharmacy : science and practice · 2023
- Metaraminol-induced coronary vasospasm masquerading as ST-elevation myocardial infarction during general anaesthesia.British journal of anaesthesia · 2024
- Dose equivalence for metaraminol and noradrenaline - A retrospective analysis.Journal of critical care · 2024
via PubMed
Wikidata facts
- Subclass of
- meta-hydroxynorephedrine
- Mass
- 167.094629
- Has use
- medication
Show 7 more facts
- chemical formula
- C₉H₁₃NO₂
- defined daily dose
- 50
- medical condition treated
- hypotension
- canonical SMILES
- CC(C(C1=CC(=CC=C1)O)O)N
- isomeric SMILES
- C[C@@H]([C@@H](C1=CC(=CC=C1)O)O)N
- World Health Organisation international non-proprietary name
- metaraminol
- Commons category
- Metaraminol
via Wikidata · CC0
~3 min read
Encyclopedic overview
8 sectionsContents
- Medical uses
- Pharmacology
- Pharmacodynamics
- Chemistry
- History
- Society and culture
- Names
- References
Metaraminol, also known as metaradrine and sold under the brand name Aramine among others, is a sympathomimetic medication which is used in the prevention and treatment of hypotension (low blood pressure), particularly as a complication of anesthesia. It is given by intramuscular or intravenous administration.
Side effects of metaraminol include reflex bradycardia among others. Metaraminol is a norepinephrine releasing agent and at high doses a α1-adrenergic receptor agonist with some β-adrenergic effect. It is a substituted amphetamine and is closely related to phenylpropanolamine, ephedrine, and oxilofrine.
Excerpted from Wikipedia’s “metaraminol” article, available under the CC BY-SA 4.0 licence.
Available in 11 languages
via Wikidata sitelinks · CC0