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labetalol
Sign in to saveLabetalol is a medication used to treat high blood pressure and in long term management of angina. This includes essential hypertension, hypertensive emergencies, and hypertension of pregnancy. In essential hypertension it is generally less preferred than a number of other blood pressure medications. It can be given by mouth or by injection into a vein.
Research
2,892 papers- Labetalol.Drug intelligence & clinical pharmacy · 1983
- Clinical pharmacology of labetalol.British journal of clinical pharmacology · 1979
- Labetalol hepatotoxicity.The American journal of medicine · 1989
- Labetalol: a review of its pharmacology, pharmacokinetics, clinical uses and adverse effects.Pharmacotherapy · 1983
- Labetalol and other agents that block both alpha- and beta-adrenergic receptors.Cleveland Clinic journal of medicine · 1994
via PubMed
Article
14 sectionsContents
- Medical uses
- Special populations
- Contraindications
- Side effects
- Common
- Rare
- Pharmacology
- Mechanism of action
- Physiological action
- Pharmacokinetics
- Distribution
- Chemistry
- History
- References
Labetalol is a medication used to treat high blood pressure and in long term management of angina. This includes essential hypertension, hypertensive emergencies, and hypertension of pregnancy. In essential hypertension it is generally less preferred than a number of other blood pressure medications. It can be given by mouth or by injection into a vein.
Common side effects include low blood pressure with standing, dizziness, feeling tired, and nausea. Serious side effects may include low blood pressure, liver problems, heart failure, and bronchospasm. Use appears safe in the latter part of pregnancy and it is not expected to cause problems during breastfeeding. It works by blocking the activation of β- and α-adrenergic receptors.