xamoterol
Sign in to saveAlso known as ICI-118587
Xamoterol, sold under the brand names Corwin, Carwin, Corwil, and Xamtol among others, is a cardiac stimulant which is used in the treatment of heart failure. It acts as a selective partial agonist of the β1-adrenergic receptor with around 50% intrinsic sympathomimetic activity (ISA) (i.e., intrinsic activity). The drug has no significant β2-adrenergic receptor agonistic activity. Xamoterol provides cardiac stimulation at rest but acts as a blocker during exercise. It is taken by mouth.
Research
321 papers- Xamoterol, a beta 1-adrenoceptor partial agonist: review of the clinical efficacy in heart failure.British journal of clinical pharmacology · 1989
- Xamoterol: stabilising the cardiac beta receptor?Lancet (London, England) · 1988
- Xamoterol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use.Drugs · 1988
- The xamoterol experience in the treatment of heart failure.The American journal of cardiology · 1993
- [Xamoterol].Medicina (Florence, Italy) · 1988
via PubMed
~2 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
{{Drugbox | Verifiedfields = verified | Watchedfields = verified | verifiedrevid = 470632689 | IUPAC_name = (RS)-N-(2-{[2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino}ethyl)morpholine-4-carboxamide | image = Xamoterol.svg | image_class = skin-invert-image | width = 250px
| tradename = Corwin, Carwin, Corwil, Xamtol | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = By mouth
Excerpted from Wikipedia’s “xamoterol” article, available under the CC BY-SA 4.0 licence.