agranulocytosis
Sign in to saveAlso known as Agranulocytosis (disorder), Agranulocytosis (finding), Agranulocytosis NOS (disorder), Granulocytopenia (disorder), Granulocytopenic disorder, Granulopenia, granulocytopenia
Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count (leukopenia, most commonly of neutrophils) and thus causing neutropenia in the circulating blood. It is a severe lack of one major class of infection-fighting white blood cells. People with this condition are at very high risk of serious infections due to their suppressed immune system.
Key facts
- Medical condition.name
- Agranulocytosis
- Medical condition.field
- Hematology, immunology
- Medical condition.symptoms
- Rigors, fever, sore throat, rapid infection
- Medical condition.complications
- Sepsis
- Medical condition.causes
- Idiosyncratic reactions to certain drugs
- Medical condition.risks
- Cocaine use
- Medical condition.diagnosis
- Complete blood count, bone marrow examination
- Medical condition.differential
- Aplastic anemia, paroxysmal nocturnal hemoglobinuria, myelodysplasia, leukemia
via Wikipedia infobox
Research
29,080 papers- [Drug-induced agranulocytosis].La Revue du praticien · 2015
- [Idiosyncratic drug-induced agranulocytosis].La Revue de medecine interne · 2006
- [Agranulocytosis].Il Policlinico. Sezione pratica · 1970
- [Agranulocytosis].Nihon rinsho. Japanese journal of clinical medicine · 2001
- Drug-induced agranulocytosis.Haematologica · 1982
via PubMed
~6 min read
Encyclopedic overview
8 sectionsContents
- Signs and symptoms
- Causes
- Diagnosis
- Classification
- Treatment
- See also
- References
- External links
Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count (leukopenia, most commonly of neutrophils) and thus causing neutropenia in the circulating blood. It is a severe lack of one major class of infection-fighting white blood cells. People with this condition are at very high risk of serious infections due to their suppressed immune system.
In agranulocytosis, the concentration of granulocytes (a major class of white blood cells that includes neutrophils, basophils, and eosinophils) drops below 200 cells/mm3 of blood.
Excerpted from Wikipedia’s “agranulocytosis” article, available under the CC BY-SA 4.0 licence.