AKT3
Sign in to saveAlso known as MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
RAC-gamma serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT3 gene.
Gene data
AKT3- Name
- AKT serine/threonine kinase 3
- Type
- protein-coding
- Position
- 243,488,233–243,851,079 (−)
- Aliases
- MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
- Ensembl
- ENSG00000275199
- RefSeq RNA
- NM_001206729.2, NM_001370074.1, NM_005465.7, NM_181690.2, XM_011544014.3
- RefSeq protein
- NP_001193658.1, NP_001357003.1, NP_005456.1, NP_859029.1, XP_011542316.1
The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
AKT serine/threonine kinase 3
- Symbol
- AKT3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:243,488,233-243,851,079
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
RAC-gamma serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT3 gene.
== Function ==
Excerpted from Wikipedia’s “AKT3” article, available under the CC BY-SA 4.0 licence.