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GeneQ18034943· pop 6· linked from 309 articles

Also known as MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2

RAC-gamma serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT3 gene.

Gene data

AKT3
Name
AKT serine/threonine kinase 3
Type
protein-coding
Position
243,488,233–243,851,079 (−)
Aliases
MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
RefSeq RNA
NM_001206729.2, NM_001370074.1, NM_005465.7, NM_181690.2, XM_011544014.3
RefSeq protein
NP_001193658.1, NP_001357003.1, NP_005456.1, NP_859029.1, XP_011542316.1

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

AKT serine/threonine kinase 3

Symbol
AKT3
Biotype
Protein coding
Organism
Homo sapiens
Location
1:243,488,233-243,851,079
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

~1 min read

Encyclopedic overview

5 sections
Contents
  • Function
  • Interactions
  • References
  • Further reading
  • External links

RAC-gamma serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT3 gene.

== Function ==

Excerpted from Wikipedia’s “AKT3” article, available under the CC BY-SA 4.0 licence.

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