Structure via PubChem · Public domain (PubChem)
amifloxacin
Sign in to saveAmifloxacin is a fluoroquinolone antibiotic, which is similar in its activity to ciprofloxacin.
In the Vinony graph
Vinony's link graph records 1 inbound reference to amifloxacin, and connects out to antibiotic, digital object identifier and chemical formula.
Vinony files it under 1,4-di-hydro-7-(1-piperazinyl)-4-oxo-3-quinolinecarboxylic acids, 4-Methylpiperazin-1-yl compounds and ECHA InfoCard ID from Wikidata.
Vinony links it to 6 Wikipedia language editions.
Chemical data
- Formula
- C16H19FN4O3
- Molecular weight
- 334.35 g/mol
- IUPAC name
- 6-fluoro-1-(methylamino)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
- SMILES
- CNN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O
- InChIKey
- RUXPNBWPIRDVTH-UHFFFAOYSA-N
- XLogP
- 0.2
- Polar surface area
- 76.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
73 papers- In vitro activities of amifloxacin and two of its metabolites.Antimicrobial agents and chemotherapy · 1989
- Amifloxacin activity against well-defined gentamicin-resistant, gram-negative bacteria.Antimicrobial agents and chemotherapy · 1984
- Inhibitory and bactericidal activities of amifloxacin, a new quinolone carboxylic acid, compared with those of seven other antimicrobial agents.Clinical therapeutics · 1984
- Metabolism and disposition of amifloxacin in laboratory animals.Antimicrobial agents and chemotherapy · 1985
- Multiple-dose pharmacokinetics and safety of oral amifloxacin in healthy volunteers.Antimicrobial agents and chemotherapy · 1990
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 334.144
Show 3 more facts
- chemical formula
- C₁₆H₁₉FN₄O₃
- canonical SMILES
- CNN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O
- Commons category
- Amifloxacin
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Amifloxacin is a fluoroquinolone antibiotic, which is similar in its activity to ciprofloxacin.
==References==
Excerpted from Wikipedia’s “amifloxacin” article, available under the CC BY-SA 4.0 licence.