AP1S1
Sign in to saveAlso known as AP19, CLAPS1, EKV3, MEDNIK, SIGMA1A, WUGSC:H_DJ0747G18.2, adaptor related protein complex 1 sigma 1 subunit, adaptor related protein complex 1 subunit sigma 1
gene umano
Gene data
AP1S1- Name
- adaptor related protein complex 1 subunit sigma 1
- Type
- protein-coding
- Position
- 101,154,352–101,161,596 (+)
- Aliases
- AP19, CLAPS1, EKV3, MEDNIK, SIGMA1A
- Ensembl
- ENSG00000106367
- RefSeq RNA
- NM_001283.5, NM_057089.2
- RefSeq protein
- NP_001274.1
The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
Lysosome - Homo sapiens (human)Human immunodeficiency virus 1 infection - Homo sapiens (human)Adaptive Immune SystemHIV InfectionHost Interactions of HIV factorsDiseaseNef-mediates down modulation of cell surface receptors by recruiting them to clathrin adaptersNef mediated downregulation of MHC class I complex cell surface expressionThe role of Nef in HIV-1 replication and disease pathogenesisImmune System
via MyGene.info
Gene · Ensembl
adaptor related protein complex 1 subunit sigma 1
- Symbol
- AP1S1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:101,154,352-101,161,596
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- AP-1 complex subunit sigma-1A within the AP1 clathrin adaptor core 1W63.png
Show 8 more facts
- HomoloGene ID
- 20342
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1174
- genomic end
- 100804877
- genomic start
- 101154456
- chromosome
- human chromosome 7
- cytogenetic location
- 7q22.1
- expressed in
- amygdala
via Wikidata · CC0