APBB3
Sign in to saveAlso known as FE65L2, SRA, amyloid beta precursor protein binding family B member 3
Amyloid beta A4 precursor protein-binding family B member 3 is a protein that in humans is encoded by the APBB3 gene.
Gene data
APBB3- Name
- amyloid beta precursor protein binding family B member 3
- Type
- protein-coding
- Position
- 140,558,268–140,564,781 (−)
- Aliases
- FE65L2, SRA
- Ensembl
- ENSG00000113108
- RefSeq RNA
- NM_006051.4, NM_133172.3, NM_133173.3, NM_133174.3, NM_133175.1
- RefSeq protein
- NP_006042.3, NP_573418.2, NP_573419.2, NP_573420.2
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
via MyGene.info
Wikidata facts
- Image
- Protein APBB3 PDB 2DYQ.png
Show 5 more facts
- HomoloGene ID
- 21221
- exact match
- identifiers.org/ncbigene/10307
- genomic end
- 139973337
- cytogenetic location
- 5q31.3
- genomic start
- 139937853
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- References
- Further reading
- External links
Amyloid beta A4 precursor protein-binding family B member 3 is a protein that in humans is encoded by the APBB3 gene.
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.