APBA2
Sign in to saveAlso known as D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L, amyloid beta precursor protein binding family A member 2
Amyloid beta A4 precursor protein-binding family A member 2 is a protein that in humans is encoded by the APBA2 gene.
In the Vinony graph
Vinony's link graph records 7 inbound references to APBA2, and connects out to PubMed, human chromosome 15 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 15.
Vinony links it to 6 Wikipedia language editions.
Gene data
APBA2- Name
- amyloid beta precursor protein binding family A member 2
- Type
- protein-coding
- Position
- 28,884,449–29,118,317 (+)
- Aliases
- D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L
- Ensembl
- ENSG00000034053
- RefSeq RNA
- NM_001130414.1, NM_001353788.2, NM_001353789.2, NM_001353790.2, NM_001353791.2
- RefSeq protein
- NP_001123886.1, NP_001340717.1, NP_001340718.1, NP_001340719.1, NP_001340720.1
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
amyloid beta precursor protein binding family A member 2
- Symbol
- APBA2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:28,884,449-29,118,317
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein APBA1 PDB 1u39.png
Show 8 more facts
- HomoloGene ID
- 4021
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/321
- chromosome
- human chromosome 15
- genomic start
- 29129629
- genomic end
- 29410518
- Commons category
- APBA2
- cytogenetic location
- 15q13.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
6 sectionsContents
- Structure
- Function
- Interactions
- References
- External links
- Further reading
Amyloid beta A4 precursor protein-binding family A member 2 is a protein that in humans is encoded by the APBA2 gene.
== Structure ==
Excerpted from Wikipedia’s “APBA2” article, available under the CC BY-SA 4.0 licence.