apolipoproteins E
Sign in to saveAlso known as LDLCQ5, apolipoprotein E3, LPG, apolipoprotein E, AD2, APOE
mammalian proteins found in Homo sapiens
Protein · UniProt
Apolipoprotein E
- Gene
- APOE
- Organism
- Homo sapiens (Human)
- Length
- 317 aa
- Molecular mass
- 36,154 Da
- Evidence
- 1: Evidence at protein level
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids (PubMed:14754908, PubMed:1911868, PubMed:6860692). APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance (PubMed:14754908, PubMed:1911868, PubMed:1917954, PubMed:23620513, PubMed:2762297, PubMed:6860692, PubMed:9395455). Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment…
Swiss-Prot (reviewed) · via UniProt
Clinical Trials
46 registered- COMPLETEDApolipoprotein E Gene and Functional MRITaipei Medical University Shuang Ho Hospital · NCT01287819
- NAUNKNOWNApolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human BrainUniversity of Washington · NCT04692441
- ACTIVE_NOT_RECRUITINGRelationship Between Serum Apolipoprotein Levels and Weight Loss in Patients Undergoing Sleeve Gastrectomy for Morbid ObesityYigit DUZKOYLU · NCT07325916
- NACOMPLETEDAcute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of ADNational Taiwan Normal University · NCT05591313
- PHASE1/PHASE2COMPLETEDSafety Study of AEM-28 to Treat Refractory HypercholesterolemiaLipimetiX Development, LLC · NCT02100839
- NACOMPLETEDDo Apolipoprotein E Polymorphisms Influence Risk of Cognitive Decline by Modulating Omega-3 Fatty Acid Metabolism?Université de Sherbrooke · NCT01577004