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GeneQ18042165· pop 9· linked from 4 articles

Also known as G3a, HSPC336, NG20, apo-M, apolipoprotein M

Apolipoprotein M is an apolipoprotein and member of the lipocalin protein family that in humans is encoded by the APOM gene. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Two transcript variants encoding two different isoforms have been found for this gene, but only one of them has been fully characterized. It lacks an external amphipathic motif and is uniquely secreted t

In the Vinony graph

Within Vinony's link graph, APOM is referenced by 4 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.

It sits within the topics Genes on human chromosome 6 and Protein pages needing a picture.

Its subject is documented across 9 Wikipedia language editions.

Gene data

APOM
Name
apolipoprotein M
Type
protein-coding
Position
31,652,416–31,658,214 (+)
Aliases
G3a, HSPC336, NG20, apo-M
RefSeq RNA
NM_001256169.2, NM_019101.3, NR_045828.2, XM_006715150.4, XM_054329835.1
RefSeq protein
NP_001243098.1, NP_061974.2, XP_006715213.1, XP_054185810.1, XP_054186294.1

The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012].

via MyGene.info

Gene · Ensembl

apolipoprotein M

Symbol
APOM
Biotype
Protein coding
Organism
Homo sapiens
Location
Chr HSCHR6_MHC_MANN_CTG1:2,957,462-2,963,256
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein APOM PDB 2WEW.png
Show 8 more facts
HomoloGene ID
10308
found in taxon
Homo sapiens
genomic start
31620193
genomic end
31625987
cytogenetic location
6p21.33
expressed in
bone marrow
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • References
  • Further reading
  • External links

Apolipoprotein M is an apolipoprotein and member of the lipocalin protein family that in humans is encoded by the APOM gene. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Two transcript variants encoding two different isoforms have been found for this gene, but only one of them has been fully characterized. It lacks an external amphipathic motif and is uniquely secreted to plasma without cleavage of its terminal signal peptide. The average molecular weight is 21253 Da, and the monoisotopic molecular weight is 21239 Da.

== References ==

Excerpted from Wikipedia’s “APOM” article, available under the CC BY-SA 4.0 licence.

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