ARF4

Also known as ARF2, ADP ribosylation factor 4

ADP-ribosylation factor 4 is a protein that in humans is encoded by the ARF4 gene.

In the Vinony graph

Within Vinony's link graph, ARF4 is referenced by 6 other articles, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 3.

Its subject is documented across 7 Wikipedia language editions.

Gene data

ARF4

Name: ARF GTPase 4
Type: protein-coding
Position: 57,571,363–57,598,220 (−)
Aliases: ARF2
Ensembl: ENSG00000168374
RefSeq RNA: NM_001660.4
RefSeq protein: NP_001651.1

This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene. [provided by RefSeq, Jul 2008].