Structure via PubChem · Public domain (PubChem)
Arimoclomol
Sign in to saveArimoclomol, sold under the brand name Miplyffa, is a medication used for the treatment of Niemann–Pick disease type C. It is taken by mouth.
Chemical data
- Formula
- C14H20ClN3O3
- Molecular weight
- 313.78 g/mol
- IUPAC name
- N-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-1-oxidopyridin-1-ium-3-carboximidoyl chloride
- SMILES
- C1CCN(CC1)C[C@H](CON=C(C2=C[N+](=CC=C2)[O-])Cl)O
- InChIKey
- SGEIEGAXKLMUIZ-CYBMUJFWSA-N
- XLogP
- 1.2
- Polar surface area
- 70.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2024
- Admin. routes
- oral
- Indications
- inclusion body myositis, amyotrophic lateral sclerosis, Gaucher disease, Niemann-Pick disease type C
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 313.11931918
Show 4 more facts
- chemical formula
- C₁₄H₂₀ClN₃O₃
- canonical SMILES
- C1CCN(CC1)CC(CON=C(C2=C[N+](=CC=C2)[O-])Cl)O
- isomeric SMILES
- c1cc(c[n+](c1)[O-])C(=NOC[C@@H](CN2CCCCC2)O)Cl
- Commons category
- Arimoclomol
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
9 sectionsContents
- Medical uses
- Side effects
- Mechanism of action
- History
- Society and culture
- Legal status
- Names
- Research
- References
Arimoclomol, sold under the brand name Miplyffa, is a medication used for the treatment of Niemann–Pick disease type C. It is taken by mouth.
The most common side effects include upper respiratory tract infection, diarrhea, and decreased weight.
Excerpted from Wikipedia’s “Arimoclomol” article, available under the CC BY-SA 4.0 licence.