Structure via PubChem · Public domain (PubChem)
Chemical data
- Formula
- C14H16Cl2N4O3
- Molecular weight
- 359.2 g/mol
- IUPAC name
- 1-[[2-[(Z)-hydroxyiminomethyl]pyridin-1-ium-1-yl]methoxymethyl]pyridin-1-ium-4-carboxamide dichloride
- SMILES
- C1=CC=[N+](C(=C1)/C=N\O)COC[N+]2=CC=C(C=C2)C(=O)N.[Cl-].[Cl-]
- InChIKey
- QELSIJXWEROXOE-UHFFFAOYSA-N
- Polar surface area
- 92.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
376 papers- Effect of Oxime Encapsulation on Acetylcholinesterase Reactivation: Pharmacokinetic Study of the Asoxime-Cucurbit[7]uril Complex in Mice Using Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry.Molecular pharmaceutics · 2021
- Asoxime (HI-6) impact on dogs after one and tenfold therapeutic doses: assessment of adverse effects, distribution, and oxidative stress.Environmental toxicology and pharmacology · 2011
- Enhancing oxime efficacy into brain using ultrasound to counteract nerve agent exposure.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025
- Modulation of ionising radiation generated oxidative stress by HI-6 (asoxime) in a laboratory rat model.Neuro endocrinology letters · 2010
- Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology.International journal of molecular sciences · 2012
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 358.059945732
Show 3 more facts
- chemical formula
- C₁₄H₁₆Cl₂N₄O₃
- canonical SMILES
- c1cc[n+](c(c1)/C=N/O)COC[n+]2ccc(cc2)C(=O)N.[Cl-].[Cl-]
- isomeric SMILES
- Cl.Cl.[NH-]C(=O)c1cc[n+](COCN2C=CC=C/C2=C/N=O)cc1
Sources (1)
via Wikidata · CC0