BACH2
Sign in to saveAlso known as BTBD25, BTB domain and CNC homolog 2, IMD60
gen de la especie Homo sapiens
Gene data
BACH2- Name
- BACH transcriptional regulator 2
- Type
- protein-coding
- Position
- 89,926,528–90,296,982 (−)
- Aliases
- BTBD25, IMD60
- Ensembl
- ENSG00000112182
- RefSeq RNA
- NM_001170794.2, NM_021813.4
- RefSeq protein
- NP_001164265.1, NP_068585.1
Enables sequence-specific double-stranded DNA binding activity. Involved in primary adaptive immune response involving T cells and B cells. Located in cytosol and nucleoplasm. Implicated in immunodeficiency 60. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
negative regulation of transcription by RNA polymerase IInegative regulation of transcription by RNA polymerase IIregulation of DNA-templated transcriptionregulation of transcription by RNA polymerase IIregulation of transcription by RNA polymerase IIprimary adaptive immune response involving T cells and B cells
Molecular function
RNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription repressor activity, RNA polymerase II-specificDNA bindingDNA-binding transcription factor activityprotein binding
Pathways
via MyGene.info
Gene · Ensembl
BACH transcriptional regulator 2
- Symbol
- BACH2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:89,926,528-90,296,982
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- 3ohu.png
Show 8 more facts
- HomoloGene ID
- 7240
- genetic association
- celiac disease
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/60468
- genomic end
- 90296843
- genomic start
- 90636248
- chromosome
- human chromosome 6
- cytogenetic location
- 6q15
via Wikidata · CC0