Structure via PubChem · Public domain (PubChem)
balofloxacin
Sign in to saveBalofloxacin (INN) is a fluoroquinolone antibiotic. It is sold under the brand name Q-Roxin in Korea, and under various names in India. It is not approved by the FDA for use in the United States.
Chemical data
- Formula
- C20H24FN3O4
- Molecular weight
- 389.4 g/mol
- IUPAC name
- 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-oxoquinoline-3-carboxylic acid
- SMILES
- CNC1CCCN(C1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
- InChIKey
- MGQLHRYJBWGORO-UHFFFAOYSA-N
- XLogP
- 0.6
- Polar surface area
- 82.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
58 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 389.175
Show 3 more facts
- chemical formula
- C₂₀H₂₄FN₃O₄
- canonical SMILES
- CNC1CCCN(C1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
- Commons category
- Balofloxacin
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Pharmacodynamics
- Side Effects
- See also
- References
Balofloxacin (INN) is a fluoroquinolone antibiotic. It is sold under the brand name Q-Roxin in Korea, and under various names in India. It is not approved by the FDA for use in the United States.
== Pharmacodynamics == Balofloxacin is a fluoroquinolone that has a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-negative bacteria, with enhanced activity against Gram positive bacteria, including MRSA and Streptococcus pneumoniae. It functions by inhibiting the action of DNA-gyrase, preventing bacterial cells from reproducing or repairing themselves, resulting in cellular death.
Excerpted from Wikipedia’s “balofloxacin” article, available under the CC BY-SA 4.0 licence.
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