Skip to content
Vinony
English
EnglishDeutschEspañolFrançaisItalianoNederlandsPortuguêsSvenskaالعربية
GeneQ14908060· pop 5· linked from 95 articles

BAMBI

Sign in to save

Also known as NMA, BMP and activin membrane-bound inhibitor, BMP and activin membrane bound inhibitor

BMP and activin membrane-bound inhibitor homolog, also known as BAMBI, is a protein which in humans is encoded by the BAMBI gene.

Gene data

BAMBI
Name
BMP and activin membrane bound inhibitor
Type
protein-coding
Position
28,677,510–28,684,890 (+)
Aliases
NMA
Ensembl
ENSG00000095739
RefSeq RNA
NM_012342.3
RefSeq protein
NP_036474.1

This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008].

Gene Ontology

Pathways

Wnt signaling pathway - Homo sapiens (human)TGF-beta signaling pathway - Homo sapiens (human)Signal TransductionSignaling by TGF-beta Receptor ComplexDownregulation of TGF-beta receptor signalingTGF-beta receptor signaling activates SMADsSignaling by TGFB family membersTGF-beta receptor signaling in skeletal dysplasiasTGF-beta Receptor Signaling

via MyGene.info

Gene · Ensembl

BMP and activin membrane bound inhibitor

Symbol
BAMBI
Biotype
Protein coding
Organism
Homo sapiens
Location
10:28,677,510-28,684,890
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
8215
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/25805
chromosome
human chromosome 10
genomic start
28677510
genomic end
28682932
cytogenetic location
10p12.1
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • Function
  • References
  • Further reading
  • External links

BMP and activin membrane-bound inhibitor homolog, also known as BAMBI, is a protein which in humans is encoded by the BAMBI gene.

== Function ==

Excerpted from Wikipedia’s “BAMBI” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0