BCL11B
Sign in to saveAlso known as ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, RIT1
B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene.
Gene data
BCL11B- Name
- BCL11 transcription factor B
- Type
- protein-coding
- Aliases
- ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, IDDFSTA, IMD49, RIT1
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013].
via MyGene.info
Gene · Ensembl
BCL11 transcription factor B
- Symbol
- BCL11B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:99,169,287-99,272,197
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 10974
- exact match
- identifiers.org/ncbigene/64919
- genomic end
- 99272197
- genomic start
- 99635624
- cytogenetic location
- 14q32.2
Sources (3)
via Wikidata · CC0
~3 min read
Article
8 sectionsContents
- Gene location
- Function
- Interactions
- Pathology
- Research projects
- References
- Further reading
- External links
B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene.
== Gene location == BCL11B is located on human chromosome 14p32.2. The mouse analogue is called Rit1 or Bcl11b and is located on mouse chromosome 12.
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