Becaplermin
Sign in to saveAlso known as PDGF B-chain, platelet-derived growth factor BB, PDG109, Platelet-derived growth factor B chain precursor, PDGF-2, c-sis, Regranex, Platelet-derived growth factor beta polypeptide
farmaco
Key facts
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 458285090
- Drug.tradename
- Regranex
- Drug.MedlinePlus
- a699049
- Drug.routes_of_administration
- Topical
- Drug.ATC_prefix
- A01
- Drug.ATC_suffix
- AD08
- Drug.ATC_supplemental
- ,
- Drug.legal_US
- Rx-only
- Drug.CAS_number
- 165101-51-9
- Drug.DrugBank
- DB00102
- Drug.UNII
- 1B56C968OA
- Drug.ChEMBL
- 1201556
- Drug.ChemSpiderID
- none
via Wikipedia infobox
Chemical data
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Protein
- First approval
- 1997
- Admin. routes
- parenteral, topical
- Indications
- Skin ulcer, diabetic foot, ulcer disease
via ChEMBL · EBI
Research
5,114 papers- Becaplermin gel in the treatment of diabetic neuropathic foot ulcers.Clinical interventions in aging · 2008
- Becaplermin: recombinant platelet derived growth factor, a new treatment for healing diabetic foot ulcers.Expert opinion on biological therapy · 2002
- Benefit-risk assessment of becaplermin in the treatment of diabetic foot ulcers.Drug safety · 2010
- Protein detection using proximity-dependent DNA ligation assays.Nature biotechnology · 2002
- Bone-derived PDGF-BB drives brain vascular calcification in male mice.The Journal of clinical investigation · 2023
via PubMed
Wikidata facts
- Subclass of
- platelet-derived growth factor complex
- Has use
- medication
Show 3 more facts
- World Health Organisation international non-proprietary name
- becaplermin
- medical condition treated
- venous ulcer
- has characteristic
- biopharmaceutical
via Wikidata · CC0
Article · Italiano
Becaplermin è il principio attivo di indicazione specifica contro le ulcere (specialmente quelle diabetiche neuropatiche), il farmaco non è commercializzato in Italia. Si trova soto forma di pomata ad uso topico con il nome Regranex (Janssen - Cilag) ed è un fattore di crescita ricombinante, il PDGF (Platelet-derived Growth Factor) prodotto in Saccharomyces cerevisae.
Abstract from DBpedia / Wikipedia · CC BY-SA