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benzobarbital
Sign in to saveBenzobarbital (Benzonal) is a barbiturate derivative. It has anticonvulsant effects and has been used for the treatment of epilepsy.
In the Vinony graph
Within Vinony's link graph, benzobarbital is referenced by 492 other articles, and connects out to benzodiazepine drug, isovaleric acid and allopregnanolone.
It is catalogued under topics including Barbiturates, Chemical pages without DrugBank identifier and Drugboxes which contain changes to verified fields.
Its subject is documented across 12 Wikipedia language editions.
Chemical data
- Formula
- C19H16N2O4
- Molecular weight
- 336.3 g/mol
- IUPAC name
- 1-benzoyl-5-ethyl-5-phenyl-1,3-diazinane-2,4,6-trione
- SMILES
- CCC1(C(=O)NC(=O)N(C1=O)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
- InChIKey
- QMOWPJIFTHVQMB-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 83.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
67 papers- [Photosensitization and photoprotection by some drugs, metabolites and other compounds].Biofizika · 1997
- [Pharmacokinetic aspects of anticonvulsant therapy with benzonal].Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) · 1988
- [Effect of anticonvulsants on convulsions induced by kynurenine, quinolinic acid, strychnine and corazole].Biulleten' eksperimental'noi biologii i meditsiny · 1981
- [Inhibition by local anesthetics and barbiturates of the active transport of H+ in the synaptic vesicle membranes of the brain].Biulleten' eksperimental'noi biologii i meditsiny · 1989
- [A method for stimulating the protective mechanisms of the gastric mucosa in peptic ulcer].Eksperimental'naia i klinicheskaia farmakologiia · 1997
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 336.111
Show 4 more facts
- Commons category
- Benzobarbital
- subject has role
- antiarrhythmic agent
- chemical formula
- C₁₉H₁₆N₂O₄
- canonical SMILES
- CCC1(C(=O)NC(=O)N(C1=O)C(=O)C2=CC=CC=C2)C3=CC=CC=C3
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Benzobarbital (Benzonal) is a barbiturate derivative. It has anticonvulsant effects and has been used for the treatment of epilepsy.
It has similar liver enzyme inducing effects to the closely related drug phenobarbital, which may be exploited in some clinical applications.
Excerpted from Wikipedia’s “benzobarbital” article, available under the CC BY-SA 4.0 licence.