Structure via PubChem · Public domain (PubChem)
butalbital
Sign in to saveAlso known as alisobumal, allylbarbituric acid, itobarbital, tetrallobarbital, 5-isobutyl-5-allylbarbituric acid, 5-(2-methylpropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione, 5-allyl-5-isobutyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-(2-methylpropyl)barbituric acid
Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) (as butalbital/acetaminophen) or aspirin, for the treatment of pain and headache. The various formulations combined with codeine are FDA-approved for the treatment of tension headaches. Butalbital has the same chemical formula as talbutal but a different structure—namely, 5-allyl-5-isobutylbarbituric acid.
Chemical data
- Formula
- C11H16N2O3
- Molecular weight
- 224.26 g/mol
- IUPAC name
- 5-(2-methylpropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
- SMILES
- CC(C)CC1(C(=O)NC(=O)NC1=O)CC=C
- InChIKey
- UZVHFVZFNXBMQJ-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 75.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1983
- Admin. routes
- oral
- Indications
- migraine disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- barbiturates
- Mass
- 224.116
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₁H₁₆N₂O₃
- medical condition treated
- headache
- canonical SMILES
- CC(C)CC1(C(=O)NC(=O)NC1=O)CC=C
- World Health Organisation international non-proprietary name
- butalbital
- Commons category
- Butalbital
- has characteristic
- bitterness
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Available forms
- Contraindications
- Side effects
- Interactions
- References
- External links
Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) (as butalbital/acetaminophen) or aspirin, for the treatment of pain and headache. The various formulations combined with codeine are FDA-approved for the treatment of tension headaches. Butalbital has the same chemical formula as talbutal but a different structure—namely, 5-allyl-5-isobutylbarbituric acid.
==Available forms==
Excerpted from Wikipedia’s “butalbital” article, available under the CC BY-SA 4.0 licence.