Structure via PubChem · Public domain (PubChem)
butalbital
Sign in to saveAlso known as alisobumal, allylbarbituric acid, itobarbital, tetrallobarbital, 5-isobutyl-5-allylbarbituric acid, 5-(2-methylpropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione, 5-allyl-5-isobutyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5-allyl-5-(2-methylpropyl)barbituric acid
Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) (as butalbital/acetaminophen) or aspirin, for the treatment of pain and headache. The various formulations combined with codeine are FDA-approved for the treatment of tension headaches. Butalbital has the same chemical formula as talbutal but a different structure—namely, 5-allyl-5-isobutylbarbituric acid.
In the Vinony graph
Vinony's link graph records 523 inbound references to butalbital, and connects out to Paracetamol, benzodiazepine drug and alphenal.
Vinony files it under Allyl compounds, Barbiturates and CYP3A4 inducers.
Vinony links it to 15 Wikipedia language editions.
Chemical data
- Formula
- C11H16N2O3
- Molecular weight
- 224.26 g/mol
- IUPAC name
- 5-(2-methylpropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione
- SMILES
- CC(C)CC1(C(=O)NC(=O)NC1=O)CC=C
- InChIKey
- UZVHFVZFNXBMQJ-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 75.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1983
- Admin. routes
- oral
- Indications
- migraine disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- barbiturates
- Mass
- 224.116
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₁H₁₆N₂O₃
- medical condition treated
- headache
- canonical SMILES
- CC(C)CC1(C(=O)NC(=O)NC1=O)CC=C
- World Health Organisation international non-proprietary name
- butalbital
- Commons category
- Butalbital
- has characteristic
- bitterness
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Available forms
- Contraindications
- Side effects
- Interactions
- References
- External links
Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as paracetamol (acetaminophen) (as butalbital/acetaminophen) or aspirin, for the treatment of pain and headache. The various formulations combined with codeine are FDA-approved for the treatment of tension headaches. Butalbital has the same chemical formula as talbutal but a different structure—namely, 5-allyl-5-isobutylbarbituric acid.
==Available forms==
Excerpted from Wikipedia’s “butalbital” article, available under the CC BY-SA 4.0 licence.