CACNA2D3
Sign in to saveAlso known as HSA272268, calcium voltage-gated channel auxiliary subunit alpha2delta 3
Calcium channel, voltage-dependent, alpha 2/delta subunit 3 is a protein that in humans is encoded by the CACNA2D3 gene on chromosome 3 (locus 3p21.1).
Gene data
CACNA2D3- Name
- calcium voltage-gated channel auxiliary subunit alpha2delta 3
- Type
- protein-coding
- Aliases
- HSA272268
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 74929
- exact match
- identifiers.org/ncbigene/55799
- genomic start
- 54156574
- genomic end
- 55108584
- cytogenetic location
- 3p21.1-p14.3
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Article
7 sectionsContents
- Function
- Clinical significance
- Breast cancer
- Gastric cancer
- References
- External links
- Further reading
Calcium channel, voltage-dependent, alpha 2/delta subunit 3 is a protein that in humans is encoded by the CACNA2D3 gene on chromosome 3 (locus 3p21.1).
== Function ==