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carbarsone

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carbarsone

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Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections. It was available for amebiasis in the United States as late as 1991. Thereafter, it remained available as a turkey feed additive for increasing weight gain and controlling histomoniasis (blackhead disease).

Chemical data

Formula
C7H9AsN2O4
Molecular weight
260.08 g/mol
IUPAC name
[4-(carbamoylamino)phenyl]arsonic acid
SMILES
C1=CC(=CC=C1NC(=O)N)[As](=O)(O)O
InChIKey
WWXBHTZSYYGCSG-UHFFFAOYSA-N
Polar surface area
113 Ų
H-bond donors
4
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of
anilides
Mass
259.978
Show 2 more facts
chemical formula
C₇H₉AsN₂O₄
canonical SMILES
C1=CC(=CC=C1NC(=O)N)[As](=O)(O)O
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

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Contents
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Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections. It was available for amebiasis in the United States as late as 1991. Thereafter, it remained available as a turkey feed additive for increasing weight gain and controlling histomoniasis (blackhead disease).

Carbarsone is one of four arsenical animal drugs approved by the U.S. Food and Drug Administration for use in poultry and/or swine, along with nitarsone, arsanilic acid, and roxarsone. In September 2013, the FDA announced that Zoetis and Fleming Laboratories would voluntarily withdraw current roxarsone, arsanilic acid, and carbarsone approvals, leaving only nitarsone approvals in place. In 2015 FDA withdrew the approval of using nitarsone in animal feeds. The ban came into effect at the end of 2015.

Excerpted from Wikipedia’s “carbarsone” article, available under the CC BY-SA 4.0 licence.

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