Dehydroemetine
Sign in to saveDehydroemetine is a synthetically produced antiprotozoal agent similar to emetine in its anti-amoebic properties and structure (they differ only in a double bond next to the ethyl substituent), but it produces fewer side effects. In the United States, it is manufactured by Roche.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 478.283
Show 5 more facts
- chemical formula
- C₂₉H₃₈N₂O₄
- canonical SMILES
- CCC1=C(CC2C3=CC(=C(C=C3CCN2C1)OC)OC)CC4C5=CC(=C(C=C5CCN4)OC)OC
- isomeric SMILES
- CCC1=C(C[C@H]2NCCC3=CC(OC)=C(OC)C=C23)C[C@@H]4N(CCC5=C4C=C(OC)C(OC)=C5)C1
- NCI Thesaurus ID
- C418
- defined daily dose
- 60
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Encyclopedic overview
5 sectionsContents
- Mechanism
- Uses
- Amoebic infections
- In other diseases
- References
Dehydroemetine is a synthetically produced antiprotozoal agent similar to emetine in its anti-amoebic properties and structure (they differ only in a double bond next to the ethyl substituent), but it produces fewer side effects. In the United States, it is manufactured by Roche.
==Mechanism== Its exact mechanism is not known, but in vitro it inhibits translocation.
Excerpted from Wikipedia’s “Dehydroemetine” article, available under the CC BY-SA 4.0 licence.
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