diloxanide furoate
Also known as diloxanide
Diloxanide is a medication used to treat amoeba infections. In places where infections are not common, it is a second line treatment after paromomycin when a person has no symptoms. For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. It is taken by mouth.
Chemical data
- Formula
- C14H11Cl2NO4
- Molecular weight
- 328.1 g/mol
- IUPAC name
- [4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate
- SMILES
- CN(C1=CC=C(C=C1)OC(=O)C2=CC=CO2)C(=O)C(Cl)Cl
- InChIKey
- BDYYDXJSHYEDGB-UHFFFAOYSA-N
- XLogP
- 3.4
- Polar surface area
- 59.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
121 papersvia PubMed
Article
5 sectionsContents
- Medical uses
- Adverse effects
- Pharmacology
- Society and culture
- References
Diloxanide is a medication used to treat amoeba infections. In places where infections are not common, it is a second line treatment after paromomycin when a person has no symptoms. For people who are symptomatic, it is used after treatment with metronidazole or tinidazole. It is taken by mouth.
Diloxanide generally has mild side effects. Side effects may include flatulence, vomiting, and itchiness. During pregnancy it is recommended that it be taken after the first trimester. It is a luminal amebicide meaning that it only works on infections within the intestines.