Structure via PubChem · Public domain (PubChem)
ornidazole
Sign in to saveAlso known as alpha-(chloromethyl)-2-methyl-5-nitro-1H-imidazole-1-ethanol, Ro 7-0207, 1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole, 1-(2-hydroxy-3-chloropropyl)-2-methyl-5-nitroimidazole
Ornidazole is an antibiotic used to treat protozoan infections. A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin. Ornidazole is nothing but chloro-secnidazole.
Chemical data
- Formula
- C7H10ClN3O3
- Molecular weight
- 219.62 g/mol
- IUPAC name
- 1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol
- SMILES
- CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-]
- InChIKey
- IPWKIXLWTCNBKN-UHFFFAOYSA-N
- XLogP
- 0.6
- Polar surface area
- 83.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- rectum cancer, bacterial disease, malignant colon neoplasm, amebiasis
via ChEMBL · EBI
Research
779 papers- Ornidazole.2006
- Efficacy of ornidazole for pericoronitis: a meta-analysis and systematic review.Archives of medical science : AMS · 2024
- Ornidazole Regulates Inflammatory Response and Odontogenic Differentiation of Human Dental Pulp Cells.International dental journal · 2025
- Ornidazole Reduces the Progression of Endometriosis in a Rat Model.Gynecologic and obstetric investigation · 2022
- Ornidazole-induced involuntary tremor in a Chinese woman: a rare case report and literature review.BMC neurology · 2025
via PubMed
Wikidata facts
- Mass
- 219.041
Show 5 more facts
- World Health Organisation international non-proprietary name
- ornidazole
- chemical formula
- C₇H₁₀ClN₃O₃
- canonical SMILES
- CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-]
- medical condition treated
- giardiasis
- Commons category
- Ornidazole
Sources (9)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Ornidazole is an antibiotic used to treat protozoan infections. A synthetic nitroimidazole, it is commercially obtained from an acid-catalyzed reaction between 2-methyl-5-nitroimidazole and epichlorohydrin. Ornidazole is nothing but chloro-secnidazole.
Antimicrobial spectrum is similar to that of metronidazole and is more well tolerated; however there are concerns of lower relative efficacy.
Excerpted from Wikipedia’s “ornidazole” article, available under the CC BY-SA 4.0 licence.