Structure via PubChem · Public domain (PubChem)
carbenicillin indanyl
Sign in to saveAlso known as indanyl carbenicillin, 6beta-{2-[(2,3-dihydro-1H-inden-5-yloxy)carbonyl]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylic acid, (2S,5R,6R)-6-{[3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenylpropanoyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, Indanyl carbenicillin, Carindacillin
Carindacillin (INN), also known as carbenicillin indanyl (USAN), is a penicillin antibiotic. It is a prodrug of carbenicillin.
In the Vinony graph
Vinony's link graph records 185 inbound references to carbenicillin indanyl, and connects out to antibiotic, ceftolozane/tazobactam and penicillin.
Vinony files it under Chemical articles with multiple CAS registry numbers, Chemical pages without DrugBank identifier and Chemicals using indexlabels.
Vinony links it to 10 Wikipedia language editions.
Chemical data
- Formula
- C26H26N2O6S
- Molecular weight
- 494.6 g/mol
- IUPAC name
- (2S,5R,6R)-6-[[3-(2,3-dihydro-1H-inden-5-yloxy)-3-oxo-2-phenylpropanoyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1972
- Admin. routes
- oral
- Indications
- osteomyelitis, bacterial disease
via ChEMBL · EBI
Research
29 papers- Carbenicillin Indanyl Disodium.2006
- Carbenicillin indanyl sodium, an orally active derivative of carbenicillin.Antimicrobial agents and chemotherapy · 1972
- Carbenicillin prodrugs: stability kinetics of alpha-phenyl and alpha-indanyl esters in aqueous solution.Journal of pharmaceutical sciences · 1979
- Ampicillin, carbenicillin indanyl ester, and nifuratel in the treatment of urinary infection in domiciliary practice.British journal of urology · 1975
- Double-blind comparison of carbenicillin indanyl sodium, ampicillin, and cephalexin in treatment of urinary tract infection.Antimicrobial agents and chemotherapy · 1973
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 494.151158
Show 7 more facts
- isomeric SMILES
- CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)OC4=CC5=C(CCC5)C=C4)C(=O)O)C
- canonical SMILES
- CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)OC4=CC5=C(CCC5)C=C4)C(=O)O)C
- chemical formula
- C₂₆H₂₆N₂O₆S
- World Health Organisation international non-proprietary name
- carindacillin
- subject has role
- antibiotic
- medical condition treated
- prostatitis
- Commons category
- Carindacillin
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Pharmacokinetics
- References
Carindacillin (INN), also known as carbenicillin indanyl (USAN), is a penicillin antibiotic. It is a prodrug of carbenicillin.
It is administered orally, as the sodium salt. It was formerly marketed in the United States by Pfizer under the brand name Geocillin. Pfizer withdrew Carindacillin from the U.S. market sometime after 2008.
Excerpted from Wikipedia’s “carbenicillin indanyl” article, available under the CC BY-SA 4.0 licence.
Available in 10 languages
via Wikidata sitelinks · CC0