carbimazole
Sign in to saveAlso known as Athyromazole, Ethyl 3-methyl-2-thioimidazoline-1-carboxylate, Carbethoxymethimazole, Carbimazolo, Carbinazole, Thyrostat, Carbimazol, Carbimazolum
Carbimazole (brand names Neo-Mercazole, Anti-Thyrox, etc.) is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine).
Research
1,666 papers- Carbimazole-induced pancytopaenia.British journal of hospital medicine (London, England : 2005) · 2016
- Carbimazole-induced lupus.BMJ case reports · 2013
- Carbimazole-induced acute cholestatic hepatitis.Journal of clinical gastroenterology · 1989
- Carbimazole-induced acute myeloid leukemia: A very rare case report and review of the literature.Indian journal of cancer · 2025
- Carbimazole embryopathy.Annales d'endocrinologie · 2017
via PubMed
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Encyclopedic overview
6 sectionsContents
- Medical uses
- Adverse effects
- Precautions
- Brand names
- References
- Further reading
Carbimazole (brand names Neo-Mercazole, Anti-Thyrox, etc.) is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine).
It is on the World Health Organization's List of Essential Medicines.
Excerpted from Wikipedia’s “carbimazole” article, available under the CC BY-SA 4.0 licence.
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