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carbofenotion

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carbofenotion

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Carbophenothion also known as Stauffer R 1303 as for the manufacturer, Stauffer Chemical, is an organophosphorus chemical compound. It was used as a pesticide for citrus fruits under the name of Trithion. Carbophenothion was used as an insecticide and acaricide. Although not used anymore it is still a restricted use pesticide in the United States. The chemical is identified in the US as an extremely hazardous substance according to the Emergency Planning and Community Right-to-Know Act.

Chemical data

Formula
C11H16ClO2PS3
Molecular weight
342.9 g/mol
IUPAC name
(4-chlorophenyl)sulfanylmethylsulfanyl-diethoxy-sulfanylidene-lambda5-phosphane

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
341.974
Show 3 more facts
chemical formula
C₁₁H₁₆ClO₂PS₃
canonical SMILES
CCOP(=S)(OCC)SCSC1=CC=C(C=C1)Cl
Commons category
Carbophenothion
Sources (2)

via Wikidata · CC0

~12 min read

Encyclopedic overview

13 sections
Contents
  • Introduction and history
  • Structure and properties
  • Synthesis
  • Mechanism of action
  • Metabolism
  • Efficacy and adverse effects
  • Efficacy
  • Adverse effects
  • Effects on humans
  • Effects on animals
  • Toxicity
  • References
  • External links

{{Chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 460946327 | Name = Carbophenothion | ImageFile = Carbophenothion.svg | PIN = S-{[(4-Chlorophenyl)sulfanyl]methyl} O,O-diethyl phosphorodithioate | OtherNames = Stauffer R 1303 | Section1 = | Section2 = | Section7 = }} Carbophenothion also known as Stauffer R 1303 as for the manufacturer, Stauffer Chemical, is an organophosphorus chemical compound. It was used as a pesticide for citrus fruits under the name of Trithion. Carbophenothion was used as an insecticide and acaricide. Although not used anymore it is still a restricted use pesticide in the United States. The chemical is identified in the US as an extremely hazardous substance according to the Emergency Planning and Community Right-to-Know Act.

== Introduction and history == Carbophenothion is a highly toxic organophosphate insecticide and acaricide. Organophosphates are acetylcholinesterase inhibitors and disrupt the signal transduction at the cholinergic synapse. It is classified as Restricted Use Pesticide (RUP) by the Environmental Protection Agency (EPA). Carbophenothion is used in different brands like Trithion. This pesticide contains 80% carbophenothion as its only active ingredient. Because of the widespread use of those organophosphates in the nineties in the US, it was the most common cause of agricultural poisonings.

Excerpted from Wikipedia’s “carbofenotion” article, available under the CC BY-SA 4.0 licence.

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