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carbromal

Structure via PubChem · Public domain (PubChem)

EntityQ382185· pop 16· linked from 597 articles

Carbromal is a hypnotic/sedative originally synthesized in 1909 by Bayer and subsequently marketed as Adalin. The drug was later sold by Parke-Davis in combination with pentobarbital, under the name Carbrital. As of 2015, it was still used in Hungary in combination with aminophenazone under the name Demalgon.

Chemical data

Formula
C7H13BrN2O2
Molecular weight
237.09 g/mol
IUPAC name
2-bromo-N-carbamoyl-2-ethylbutanamide
SMILES
CCC(CC)(C(=O)NC(=O)N)Br
InChIKey
OPNPQXLQERQBBV-UHFFFAOYSA-N
XLogP
1.5
Polar surface area
72.2 Ų
H-bond donors
2
H-bond acceptors
2
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
236.016
Show 4 more facts
chemical formula
C₇H₁₃BrN₂O₂
canonical SMILES
CCC(CC)(C(=O)NC(=O)N)Br
isomeric SMILES
CCC(CC)(/C(=N/C(=N)O)/O)Br
Commons category
Carbromal
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • Synthesis
  • See also
  • References

Carbromal is a hypnotic/sedative originally synthesized in 1909 by Bayer and subsequently marketed as Adalin. The drug was later sold by Parke-Davis in combination with pentobarbital, under the name Carbrital. As of 2015, it was still used in Hungary in combination with aminophenazone under the name Demalgon.

==Synthesis== center|600px|thumb|Carbromal synthesis: Literature:

Excerpted from Wikipedia’s “carbromal” article, available under the CC BY-SA 4.0 licence.

Gallery (2)