CBX8
Sign in to saveAlso known as PC3, RC1, chromobox 8
Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.
Gene data
CBX8- Name
- chromobox 8
- Type
- protein-coding
- Position
- 79,792,132–79,801,683 (−)
- Aliases
- PC3, RC1
- Ensembl
- ENSG00000141570
- RefSeq RNA
- NM_020649.3
- RefSeq protein
- NP_065700.1
Enables methylated histone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in chromatin and nucleoplasm. Part of PRC1 complex. Biomarker of esophagus squamous cell carcinoma and glioblastoma. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
negative regulation of transcription by RNA polymerase IInegative regulation of transcription by RNA polymerase IInegative regulation of transcription by RNA polymerase IIpositive regulation of cell population proliferationheterochromatin formationpositive regulation of collagen biosynthetic processpositive regulation of DNA repairnegative regulation of DNA-templated transcription
Molecular function
Pathways
via MyGene.info
Wikidata facts
- Image
- Protein CBX8 PDB 2dnv.png
Show 5 more facts
- HomoloGene ID
- 32199
- exact match
- identifiers.org/ncbigene/57332
- genomic start
- 77765931
- genomic end
- 77775482
- cytogenetic location
- 17q25.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Interactions
- References
- External links
- Further reading
Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.
==Interactions== CBX8 has been shown to interact with RING1 and MLLT1.
Connections
Q180686
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human chromosome 17
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Ensembl genome database project
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protein
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Wikidata
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gene
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chromosome
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digital object identifier
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International Standard Serial Number
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bibcode
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human genome
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Q229883
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base pair
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locus
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gene expression
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Online Mendelian Inheritance in Man
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Protein Data Bank
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Q22908627
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Entrez
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Q905695
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